Mouse S100A9 Recombinant Protein (RPPB4569)
- SKU:
- RPPB4569
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Uniprot:
- P31725
Description
| Product Name: | Mouse S100A9 Recombinant Protein |
| Product Code: | RPPB4569 |
| Size: | 10µg |
| Species: | Mouse |
| Target: | S100A9 |
| Synonyms: | Calgranulin B, 60B8AG, CAGB, CFAG, CGLB, L1AG, LIAG, MAC387, MIF, MRP14, NIF, P14, Protein S100-A9, S100 calcium-binding protein A9. |
| Source: | Escherichia Coli |
| Physical Appearance: | S100A9 is supplied as a sterile filtered clear solution. |
| Formulation: | S100A9 protein (0.5mg/ml) is supplied in 20mM Tris-HCL, pH-8, 1mM DTT and 20% Glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MANKAPSQME RSITTIIDTF HQYSRKEGHP DTLSKKEFRQ MVEAQLATFM KKEKRNEALI NDIMEDLDTN QDNQLSFEEC MMLMAKLIFA CHEKLHENNP RGHGHSHGKG CGK |
S100A9 is part of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100A9 protein is localized in the cytoplasm and/or nucleus of a wide range of cells, and participates in the regulation of several cellular processes such as cell cycle progression and differentiation. S100 genes include no less than 13 proteins which are localized as a cluster on chromosome 1q21. S100A9 is involved in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis.��
S100A9 Mouse Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 133 amino acids (1-113) and having a molecular mass of 15.2 kDa.The S100A9 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | S100A9: a calcium-binding regulatory protein of the S-100 family expressed by macrophages in acutely inflammated tissues and in chronic inflammations. May be an inhibitor of protein kinases. Also expressed in epithelial cells constitutively or induced during dermatoses. May interact with components of the intermediate filaments in monocytes and epithelial cells. Interacts with CEACAM3 in a calcium-dependent manner. |
| UniProt Protein Details: | Protein type:Calcium-binding Cellular Component: cytoplasm; cytoskeleton; extracellular region; extracellular space; membrane; nucleus; plasma membrane Molecular Function:antioxidant activity; arachidonic acid binding; calcium ion binding; metal ion binding; microtubule binding; RAGE receptor binding; zinc ion binding Biological Process: actin cytoskeleton reorganization; apoptosis; astrocyte development; autophagy; caspase activation; chemotaxis; immune system process; inflammatory response; innate immune response; leukocyte chemotaxis; leukocyte migration during inflammatory response; neutrophil chemotaxis; peptidyl-cysteine S-nitrosylation; positive regulation of blood coagulation; positive regulation of inflammatory response; positive regulation of peptide secretion; regulation of inflammatory response; regulation of integrin biosynthetic process; regulation of translation |
| UniProt Code: | P31725 |
| NCBI GenInfo Identifier: | 399173 |
| NCBI Gene ID: | 20202 |
| NCBI Accession: | P31725.3 |
| UniProt Related Accession: | P31725 |
| Molecular Weight: | 13,049 Da |
| NCBI Full Name: | Protein S100-A9 |
| NCBI Synonym Full Names: | S100 calcium binding protein A9 (calgranulin B) |
| NCBI Official Symbol: | S100a9�� |
| NCBI Official Synonym Symbols: | p14; Cagb; GAGB; L1Ag; BEE22; MRP14; 60B8Ag; AW546964�� |
| NCBI Protein Information: | protein S100-A9 |
| UniProt Protein Name: | Protein S100-A9 |
| UniProt Synonym Protein Names: | Calgranulin-B; Leukocyte L1 complex heavy chain; Migration inhibitory factor-related protein 14; MRP-14; p14; S100 calcium-binding protein A9 |
| Protein Family: | Protein |
| UniProt Gene Name: | S100a9�� |
| UniProt Entry Name: | S10A9_MOUSE |
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