Growth Factors & Cytokines Recombinant Proteins

Mouse RANKL/TNFSF11 Recombinant Protein (RPES3368)

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SKU:
RPES3368
Product Type:
Recombinant Protein
Species:
Mouse
Research Area:
Growth Factors & Cytokines

Description

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Mouse RANKL/TNFSF11 Recombinant Protein

Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thymus and lymph nodes. This cytokine can bind to TNFRSF11B/OPG andTNFRSF11A/RANK. Tnfsf11 is involved in a number of fundamental biological processes such as acting as regulator of interactions between T-cells and dendritic cells, the regulation of the T-cell-dependent immune response and enhancing bone-resorption in humoral hypercalcemia of malignancy. It augments the ability of dendritic cells to stimulate naive T-cell proliferation.

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