Growth Factors & Cytokines Recombinant Proteins
Mouse RANKL/TNFSF11 Recombinant Protein (RPES3368)
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- SKU:
- RPES3368
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Research Area:
- Growth Factors & Cytokines
Description
system_update_altDatasheet
Mouse RANKL/TNFSF11 Recombinant Protein
Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thymus and lymph nodes. This cytokine can bind to TNFRSF11B/OPG andTNFRSF11A/RANK. Tnfsf11 is involved in a number of fundamental biological processes such as acting as regulator of interactions between T-cells and dendritic cells, the regulation of the T-cell-dependent immune response and enhancing bone-resorption in humoral hypercalcemia of malignancy. It augments the ability of dendritic cells to stimulate naive T-cell proliferation.
| Product Name: | Mouse RANKL/TNFSF11 Recombinant Protein (RPES3368) |
| Product Code: | RPES3368 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | Human Cells |
| Synonyms: | Tumor necrosis factor ligand superfamily member 11,Tnfsf11,Osteoclast differentiation factor,ODF,Osteoprotegerin ligand,OPGL,Receptor activator of nuclear factor kappa-B ligand,RANKL,TNF-related activation-induced cytokine,TRANCE,CD254 |
| Accession: | O35235 |
| Sequence: | Ala73-Asp316 |
| Fusion tag: | C-6His |
| Activity: | Immobilized Human OPG-Fc(Cat: PKSH033124) at 2µg/ml(100 ?l/well) can bind Mouse RANKL-His. The ED50 of Mouse RANK L-His is 2.44ug/ml . |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse TNF-related Activation-induced Cytokine is produced by our Mammalian expression system and the target gene encoding Ala73-Asp316 is expressed with a 6His tag at the N-terminus. |
| Purity: | > 95 % as determined by SDS-PAGE |
| Mol Mass: | 28.5 kDa |
| AP Mol Mass: | 30-35 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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Human RANKL/TNFSF11 Recombinant Protein (RPES3610)
Growth Factors & Cytokines Recombinant Proteins
system_update_altDatasheetHuman RANKL/TNFSF11 Recombinant Protein CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) super