Mouse RAET1E Recombinant Protein (RPPB4389)
- SKU:
- RPPB4389
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Uniprot:
- Q9CZQ6
Description
| Product Name: | Mouse RAET1E Recombinant Protein |
| Product Code: | RPPB4389 |
| Size: | 10µg |
| Species: | Mouse |
| Target: | RAET1E |
| Synonyms: | RAE-1-epsilon,Retinoic acid early-inducible protein 1-epsilon, Raet1e. |
| Source: | Sf9 Insect cells |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | RAET1Eprotein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10%glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | LDDAHSLRCNLTIKDPTSAD LPWCDVKCSV DEITILHLNN INKTMTSGDP GKMANATGKC LTQPLNDLCQ ELRDKVSNTKVDTHKTNGYP HLQVTMIYPQ SQGQTPSATW EFNISDSYFF TFYTENMSWR SANDESGVIM NKWKDDGDLV QQLKYFIPQC RQKIDEFLKQ SKEKPRSTSR SPSITQLTST SPLPPPSHSL EHHHHHH |
| UniProt Code: | Q9CZQ6 |
RAET1E is a member of the MHC class I family. MHC class I family contains main histocompatibility complex (MHC) class I-related genes positioned in a cluster on chromosome 6q24.2-q25.3. RAET1E and RAET1G protein are different from other RAET1 proteins since they have type I membrane-spanning sequences at their C termini instead glycosylphosphatidylinositol anchor sequences.RAET1E acts as a ligand for NKG2D receptor, expressed on the surface of numerous types of immune cells, involves in innate adaptive immune reactions.RAET1E delivers signals to NK cells and advances tumor immune surveillance by inducing the growth of anti-tumor cytotoxic lymphocyte.
RAET1E produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 207 amino acids (29-227a.a.) and having a molecular mass of 23.5kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).RAET1E is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
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