Mouse Podoplanin/PDPN Recombinant Protein (His Tag）
- SKU:
- RPES6101
- Product Type:
- Recombinant Protein
- Species:
- Mouse
Description
| Product Name: | Mouse Podoplanin/PDPN Recombinant Protein (His Tag） |
| Product Code: | RPES6101 |
| Size: | 20µg |
| Species: | Mouse |
| Expression Host: | HEK293 Cells |
| Synonyms: | Gp38, OTS-8, RANDAM-2, T1-alpha, T1a, T1alpha, Podoplanin, Aggrus, Glycoprotein 38, PA2.26 antigen |
| Mol Mass: | 15.4 kDa |
| AP Mol Mass: | 20-30 kDa |
| Tag: | C-His |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | Please contact us for more information. |
| Bio Activity: | Testing in progress |
| Sequence: | Met 1-Leu 141 |
| Accession: | Q62011 |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution: | Please refer to the printed manual for detailed information. |
| Background: | Podoplanin, also known as PDPN, is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined. Alternatively spliced transcript variants encoding different isoforms have been identified.PDPN is a mucin-type glycoprotein negatively charged by extensive O-glycosylation and a high content of sialic acid, which expresses the adhesive property. It is selectively expressed in lymphatic endothelium as well as lymphangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. PDPN may contribute to form odontoblastic fiber or function as the anchorage to the tooth development and in proliferating epithelial cells of cervical loop and apical bud. The intensity of podoplanin expression is negatively correlated with the expression of CD34 and factor VIII. Podoplanin would be useful as a diagnostic marker for epithelioid hemangioendothelioma in liver tumors. |
Related Products
Mouse Podoplanin/PDPN Recombinant Protein (RPES0869)
Cell Biology Recombinant Proteins
system_update_altDatasheetMouse Podoplanin/PDPN Recombinant Protein Podoplanin belongs to the podoplanin family, also known as Glycoprotein 38. Podoplanin is synthesized as a 172 amino acid (aa)
Mouse Podoplanin/PDPN Recombinant Protein (RPES3418)
system_update_altDatasheetMouse Podoplanin/PDPN Recombinant Protein Podoplanin, also known as PDPN, is a type-I integral membrane glycoprotein with diverse distribution in human tissues. T
Mouse Podoplanin/PDPN Recombinant Protein (RPES3397)
system_update_altDatasheetMouse Podoplanin/PDPN Recombinant Protein Podoplanin, also known as PDPN, is a type-I integral membrane glycoprotein with diverse distribution in human tissues. T
Human Podoplanin/PDPN Recombinant Protein (RPES2251)
Cell Biology Recombinant Proteins
system_update_altDatasheetHuman Podoplanin/PDPN Recombinant Protein Podoplanin is a type-1 transmembrane protein that belongs to Podoplanin family. PDPN expressed in various specialized cell type
Rat Podoplanin/PDPN Recombinant Protein (RPES4000)
system_update_altDatasheetRat Podoplanin/PDPN Recombinant Protein Podoplanin, also known as PDPN, is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The