Growth Factors & Cytokines Recombinant Proteins

Mouse PDGF-BB Recombinant Protein (RPES0906)

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SKU:
RPES0906
Product Type:
Recombinant Protein
Species:
Mouse
Research Area:
Growth Factors & Cytokines

Description

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Mouse PDGF-BB Recombinant Protein

Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. As growth factor?it plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. It is required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. PDGFB also plays an important role in wound healing.

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