Description
system_update_altDatasheet
Mouse PCSK9/NARC1 Recombinant Protein
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis.PCSK9 also plays a role in neural development.
| Product Name: | Mouse PCSK9/NARC1 Recombinant Protein (RPES2648) |
| Product Code: | RPES2648 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | Human Cells |
| Synonyms: | Proprotein Convertase Subtilisin/Kexin Type 9, Neural Apoptosis-Regulated Convertase 1, NARC-1, Proprotein Convertase 9, PC9, Subtilisin/Kexin-Like Protease PC9, Pcsk9, Narc1,FH3,HCHOLA3,Narc1 |
| Accession: | Q80W65 |
| Sequence: | Gln35-Gln155&Ser156-Gln692 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse Proprotein Convertase Subtilisin/Kexin Type 9 is produced by our Mammalian expression system and the target gene encoding Gln35-Gln155&Ser156-Gln692 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by SDS-PAGE |
| Mol Mass: | 14&57.4 |
| AP Mol Mass: | 19&60 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 50mM HEPES,150mM NaCl,20%Glycerol,pH 7.4. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Mouse |
Research Area: |
Cell Death |