Mouse NK1.1 Monoclonal Antibody (Biotin Conjugated) [PK136](AGEL0011)

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SKU:
AGEL0011
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PK136
Conjugation:
Biotin
Applications:
FC

Description

system_update_altDatasheet
Antibody Name:Mouse NK1.1 Monoclonal Antibody (Biotin Conjugated)
Antibody Code:AGEL0011
Size:100µg
Clone:PK136
Synonyms:Killer cell lectin-like receptor subfamily B member 1C, Klrb1c, CD161 antigen-like family member C, Ly-55c, NK1.1, NKR-P1.9, NKR-P1C, NKR-P1 40, CD161c
Host Species:Mouse
Species Reactivity:Mouse
Applications:FC
Concentration:1mg/mL
Isotype:IgG2a
Conjugation:Biotin
Applications:FC
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:PBS with 0.05% Proclin300, 1% BSA
Storage:Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Gene ID:17059
Uniprot:P27814
Background:NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.
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