Cell Biology Recombinant Proteins
Mouse MOG Recombinant Protein (RPES3039)
- SKU:
- RPES3039
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Research Area:
- Cell Biology
Description
Mouse MOG Recombinant Protein
Myelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein belonging to immunoglobulin superfamily, and contains an Ig-like domain followed by two potential membrane-spanning regions. MOG is expressed only in the CNS with very low content (approximately 0.1% total proteins) in oligodendrogliocyte membrane. Three possible functions for MOG were suggested: (a) a cellular adhesive molecule, (b) a regulator of oligodendrocyte microtubule stability, and (c) a mediator of interactions between myelin and the immune system, in particular, the complement cascade. A direct interaction might exist between the membrane-associated regions of MOG and the myelin-specific glycolipid galactocerebroside (Gal-C), and such an interaction may have important consequences regarding the membrane topology and function of both molecules. It is considered that MOG is an autoantigen capable to produce a demyelinating multiple sclerosis-like disease in experimental animals.
| Product Name: | Mouse MOG Recombinant Protein (RPES3039) |
| Product Code: | RPES3039 |
| Size: | 20µg |
| Species: | Mouse |
| Expressed Host: | E.coli |
| Synonyms: | B230317G11Rik |
| Accession: | Q61885 |
| Sequence: | Gly 29-Thr 156 |
| Fusion tag: | C-His |
| Endotoxin: | Please contact us for more information. |
| Protein Construction: | A DNA sequence encoding the mouse MOG (Q61885) extracellular domain (Gly 29-Thr 156) was expressed, with a C-terminal polyhistidine tag. |
| Purity: | > 97 % as determined by SDS-PAGE |
| Mol Mass: | 16 kDa |
| AP Mol Mass: | 16 kDa |
| Formulation: | Lyophilized from sterile PBS, pH 5.5 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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