Mouse MME/CD10/Neprilysin Recombinant Protein (His tag)

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SKU:
RPES5775
Product Type:
Recombinant Protein
Species:
Mouse

Description

Product Name:Mouse MME/CD10/Neprilysin Recombinant Protein (His tag)
Product Code:RPES5775
Size:20µg
Species:Mouse
Expression Host:E.coli
Synonyms:Atriopeptidase, CALLA, Enkephalinase, EPN, NEP, Neprilysin, neprilysin-390, neprilysin-411, SFE, Skin fibroblast elastase
Mol Mass:31.79 kDa
AP Mol Mass:32 kDa
Tag:N-His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:Please contact us for more information.
Bio Activity:Testing in progress
Sequence:Met 461-Trp 750
Accession:Q61391
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:CD10, also known as neprilysin, common acute lymphoblastic leukemia antigen (CALLA), or neutral endopeptidase (NEP), is a zinc-dependent transmembrane metallo-endopeptidase. CD10 cleaves peptides at the N-terminal side of hydrophobic amino acid residues and deactivates a variety of signaling peptides. CD10 was shown to be one of the markers for a natural killer cell-restricted progenitor in fetal and adult tissues. Studies also suggest CD10 as a phenotypic marker to distinguish mature neutrophils from immature neutrophils in patients with inflammation. In addition, CD10+GPR77+ carcinoma-associated fibroblasts (CAFs) promote tumor formation and chemoresistance.
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