Meteorin is a novel secreted protein that is expressed in undifferentiated neural progenitors and in the astrocyte lineage, including radial glia. It plays important roles in the differentiation of glial cells and also in axonal network formation during neurogenesis. Meteorin selectively promoted astrocyte formation from mouse cerebrocortical neurospheres in differentiation culture, whereas it induced cerebellar astrocytes to become radial glia. Meteorin also induced axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia.
Product Name:
Mouse Meteorin/METRN Recombinant Protein (RPES0839)
Product Code:
RPES0839
Size:
20µg
Species:
Mouse
Expressed Host:
HEK293 Cells
Synonyms:
1810034B16Rik,Hyrac
Accession:
Q8C1Q4-1
Sequence:
Gly22-Asp291
Fusion tag:
N-Fc
Endotoxin:
<1.0 EU per µg of the protein as determined by the LAL method.
Protein Construction:
A DNA sequence encoding the mouse METRN (Q8C1Q4-1) (Gly22-Asp291) was expressed with the fused Fc region of human IgG1 at the N-terminus.
Purity:
> 85 % as determined by SDS-PAGE
Mol Mass:
58.4 kDa
AP Mol Mass:
57 kDa
Formulation:
Lyophilized from sterile PBS, pH 7.4
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
