Description
| Product Name: | Mouse MESDC2 Recombinant Protein |
| Product Code: | RPPB3962 |
| Size: | 10µg |
| Species: | Mouse |
| Target: | MESDC2 |
| Synonyms: | LDLRchaperone MESD, Mesoderm development candidate 2, Mesoderm development protein,Mesdc2, Mesd. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | MESDC2protein solution (1mg/ml) containing Phosphate Buffered Saline (pH 7.4) and 10%glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greaterthan 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSADTPGEA TPPPRKKKDI RDYNDADMAR LLEQWEKDDD IEEGDLPEHKRPSAPIDFSK LDPGKPESIL KMTKKGKTLM MFVTVSGNPT EKETEEITSL WQGSLFNANY DVQRFIVGSDRAIFMLRDGS YAWEIKDFLV SQDRCAEVTL EGQMYPGKGG GSKEKNKTKP EKAKKKEGDPKPRASKEDNR AGSRREDL |
| UniProt Code: | Q9ERE7 |
Mesoderm development candidate 2 (MESDC2) is required for formation of the primitive streak and mesoderm during embryogenesis. MESDC2 binds to the Wnt co-receptors LRP5 and LRP6 in the endoplasmic reticulum and is required for their proper folding and cell surface expression.
MESDC2 Mouse Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 218 amino acids (30-224 a.a) andhaving a molecular mass of 24.4kDa.�MESDC2 is fused to a 23 amino acid His-tagat N-terminus & purified by proprietary chromatographic techniques.