Description
system_update_altDatasheet
Mouse M-CSF/CSF1 Recombinant Protein
Macrophage colony-stimulating factor 1µm-csf?is a single-pass type I membrane protein . It is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor, M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.
| Product Name: | Mouse M-CSF/CSF1 Recombinant Protein (RPES2314) |
| Product Code: | RPES2314 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | Human Cells |
| Synonyms: | Macrophage colony-stimulating factor 1,CSF-1,MCSF,Csf1,Csfm |
| Accession: | P07141 |
| Sequence: | Lys33-Glu262 |
| Activity: | Measured in a cell proliferation assay using M?NFS?60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 0.04-0.2 ng/ml. |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse Macrophage colony-stimulating factor 1 is produced by our Mammalian expression system and the target gene encoding Lys33-Glu262 is expressed. |
| Purity: | > 95 % as determined by SDS-PAGE |
| Mol Mass: | 26.0 kDa |
| AP Mol Mass: | 43 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 0. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Mouse |
Research Area: |
Immunology |