Growth Factors & Cytokines Recombinant Proteins

Mouse LGALS8 Recombinant Protein (RPPB0289)

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SKU:
RPPB0289
Product Type:
Recombinant Protein
Species:
Mouse
Uniprot:
Q9JL15
Research Area:
Growth Factors & Cytokines

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Mouse LGALS8 Recombinant Protein
Product Code:RPPB0289
Size:10µg
Species:Mouse
Target:LGALS8
Synonyms:Galectin-8, Gal-8, LGALS-8, AI326142, D13Ertd524e, 1200015E08Rik.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The LGALS8 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMLSLNNL QNIIYNPIIP YVGTITEQLK PGSLIVIRGH VPKDSERFQV DFQLGNSLKP RADVAFHFNP RFKRSSCIVC NTLTQEKWGW EEITYDMPFR KEKSFEIVFM VLKNKFQVAV NGRHVLLYAH RISPEQIDTV GIYGKVNIHS IGFRFSSDLQSMETSALGLT QINRENIQKP GKLQLSLPFE ARLNASMGPG RTVVIKGEVN TNARSFNVDL VAGKTRDIAL HLNPRLNVKA FVRNSFLQDA WGEEERNITC FPFSSGMYFE MIIYCDVREF KVAINGVHSL EYKHRFKDLS SIDTLSVDGD IRLLDVRSW
Biological Activity:The ED50 for this effect is ? 2ug/ml. Measured by its ability to agglutinate human red blood cells.

LGALS8 is a prostate-specific antigen that is solely overexpressed in malignant tumors and thus is a supplementary specific identifier of malignancies. LGALS8 is part of the galectin gene family which facilitates both cell-cell and cell matrix interactions in a method parallel to the selectin subgroup of C-type lectins.

LGALS8 mouse Recombinant produced E. coli is a single polypeptide chain containing 339 amino acids (1-316) and having a molecular mass of 38kDa.LGALS8 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:galectin-8: 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Cell adhesion

Chromosomal Location of Human Ortholog: 13 A1|13 4.64 cM

Cellular Component: cytoplasm; cytoplasmic vesicle; cytosol; membrane

Molecular Function:carbohydrate binding; integrin binding

Biological Process: autophagy; plasma cell differentiation; T cell costimulation

UniProt Code:Q9JL15
NCBI GenInfo Identifier:312261230
NCBI Gene ID:56048
NCBI Accession:NP_001185972.1
UniProt Related Accession:Q9JL15
Molecular Weight:36,162 Da
NCBI Full Name:galectin-8 isoform 1
NCBI Synonym Full Names:lectin, galactose binding, soluble 8
NCBI Official Symbol:Lgals8��
NCBI Official Synonym Symbols:Lgals-8; AI326142; D13Ertd524e; 1200015E08Rik��
NCBI Protein Information:galectin-8
UniProt Protein Name:Galectin-8
UniProt Synonym Protein Names:LGALS-8
Protein Family:Gallinacin
UniProt Gene Name:Lgals8��
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