Growth Factors & Cytokines Recombinant Proteins

Mouse LGALS2 Recombinant Protein (RPPB0277)

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RPPB0277

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Mouse LGALS2 Recombinant Protein
Product Code:RPPB0277
Size:10µg
Species:Mouse
Target:LGALS2
Synonyms:Galectin-2, Gal-2, Lgals2, 2200008F12Rik, AI324147.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:LGALS2 protein (1mg/ml) contains 10% glycerol, 0.1M NaCl, 1mM DTT and �20mM Tris-HCl buffer (pH 8.0).
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMSEKFEV KDLNMKPGMS LKIKGKIHND VDRFLINLGQ GKETLNLHFN PRFDESTIVC NTSEGGRWGQ EQRENHMCFS PGSEVKITIT FQDKDFKVTL PDGHQLTFPN RLGHNQLHYL SMGGLQISSF KLE
Biological Activity:Measured by its ability to agglutinate human red blood cells. The ED50 is ? 20ug/ml.

Galectin-2 or LGALS2 is a protein, part of the galectin proteins family. The galectin proteins family holds galectin proteins family lectins that mediates adhesion between cells or cells to ECM. This family also take part in pre-mRNA splicing, apoptosis & tumor progression. Galectin-2 induces apoptosis in T cells that are activated & binds to lymphotoxin-a, also can implicatate on myocardial infarction. LGALS2 from human and mouse share about 65% amino acid sequence resemblance.

LGALS2 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 153 amino acids (1-130 a.a) and having a molecular mass of 17.3kDa.LGALS2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:galectin-2: This protein binds beta-galactoside. Its physiological function is not yet known.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 15|15 E1

Molecular Function:galactoside binding

UniProt Code:Q9CQW5
NCBI GenInfo Identifier:13629138
NCBI Gene ID:107753
NCBI Accession:Q9CQW5.1
UniProt Secondary Accession:Q9CQW5,Q9D800, Q9D862,
UniProt Related Accession:Q9CQW5
Molecular Weight:17.3 kDa
NCBI Full Name:Galectin-2
NCBI Synonym Full Names:lectin, galactose-binding, soluble 2
NCBI Official Symbol:Lgals2��
NCBI Official Synonym Symbols:AI324147; 2200008F12Rik��
NCBI Protein Information:galectin-2
UniProt Protein Name:Galectin-2
Protein Family:Galectin
UniProt Gene Name:Lgals2��
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Additional Information

Product Type:
Recombinant Protein
Species:
Mouse
Uniprot:
Q9CQW5
Research Area:
Growth Factors & Cytokines
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