Mouse LAMP2 Recombinant Protein (RPPB3839)
- SKU:
- RPPB3839
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Uniprot:
- P17047
Description
| Product Name: | Mouse LAMP2 Recombinant Protein |
| Product Code: | RPPB3839 |
| Size: | 10µg |
| Species: | Mouse |
| Target: | LAMP2 |
| Synonyms: | Lysosome-associated membrane glycoprotein 2, LAMP-2,Lysosome-associated membrane protein 2, CD107 antigen-like family member B,Lysosomal membrane glycoprotein type B, LGP-B, CD107b. |
| Source: | Sf9 Insect cells |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | LAMP2 protein solution (0.5mg/ml) containing PhosphateBuffered Saline (pH 7.4) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.�Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. |
| Purity: | Greaterthan 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | LIVNLTDSKG TCLYAEWEMN FTITYETTNQ TNKTITIAVP DKATHDGSSCGDDRNSAKIM IQFGFAVSWA VNFTKEASHY SIHDIVLSYN TSDSTVFPGA VAKGVHTVKN PENFKVPLDVIFKCNSVLTY NLTPVVQKYW GIHLQAFVQN GTVSKNEQVC EEDQTPTTVA PIIHTTAPST TTTLTPTSTPTPTPTPTPTV GNYSIRNGNT TCLLATMGLQ LNITEEKVPF IFNINPATTN FTGSCQPQSA QLRLNNSQIKYLDFIFAVKN EKRFYLKEVN VYMYLANGSA FNISNKNLSF WDAPLGSSYM CNKEQVLSVS RAFQINTFNL KVQPFNVTKGQYSTAQDCSA DEDNLEHHHH HH |
The protein encoded by LAMP2 belongs to a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands LAMP2 takes part in tumor cell metastasis and in addition has a role in the protection, maintenance, and adhesion of the lysosome. The effect of alternative splicing of this gene is multiple transcript variants encoding distinct proteins.
LAMP2 Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 362 amino acids (26-379 a.a.) and having a molecular mass of 40.2kDa (Molecular size on SDS-PAGE will appear at approximately 50-70kDa).LAMP2 is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010] |
| UniProt Code: | P17047 |
| NCBI GenInfo Identifier: | 21361337 |
| NCBI Gene ID: | 1983 |
| NCBI Accession: | NP_001960 |
| UniProt Secondary Accession: | P17047,P17047 |
| UniProt Related Accession: | P17047,P55010 |
| Molecular Weight: | |
| NCBI Full Name: | eukaryotic translation initiation factor 5 |
| NCBI Synonym Full Names: | eukaryotic translation initiation factor 5 |
| NCBI Official Symbol: | EIF5�� |
| NCBI Official Synonym Symbols: | EIF-5; EIF-5A�� |
| NCBI Protein Information: | eukaryotic translation initiation factor 5 |
| UniProt Protein Name: | Eukaryotic translation initiation factor 5 |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | EIF5�� |
| UniProt Entry Name: | IF5_HUMAN |
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