Mouse Kallikrein 1/KLK1 Recombinant Protein (RPES1284)

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SKU:
RPES1284
Product Type:
Recombinant Protein
Species:
Mouse

Description

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Mouse Kallikrein 1/KLK1 Recombinant Protein

Kallikreins belongs to the family of trypsin-like serine proteases, many of which are associated with a variety of cancers. Kallikrein 1 (KLK1) is also known as tissue kallikrein and urinary kallikrein. KLK1 is synthesized as a 261 amino acid (aa) protein that contains a 18 aa signal peptide and a 241 aa proprotein. An important physiological function of KLK1 cleaves Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Kinins regulate vasodilation, blood pressure reduction, smooth muscle relaxation and contraction, pain induction and inflammation.

Product Name:Mouse Kallikrein 1/KLK1 Recombinant Protein (RPES1284)
Product Code:RPES1284
Size:10µg
Species:Mouse
Expressed Host:Human Cells
Synonyms:Glandular kallikrein K1, KAL-B, Renal kallikrein, Tissue kallikrein-6, mGK-6
Accession:P15947
Sequence:Pro19-Asp261
Fusion tag:C-His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Mouse Kallikrein-1 is produced by our Mammalian expression system and the target gene encoding Pro19-Asp261 is expressed with a 6His tag at the C-terminus.
Purity:> 95% as determined by reducing SDS-PAGE.
Mol Mass:27.9 kDa
AP Mol Mass:34-38 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM Tris,150mM NaCl,pH7.5.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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