Immunology Recombinant Proteins
Mouse Interleukin-2/IL-2 Recombinant Protein (RPES1396)
- SKU:
- RPES1396
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Research Area:
- Immunology
Description
Mouse Interleukin-2/IL-2 Recombinant Protein
Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family which includes IL-4, IL-7, IL-9, IL-15 and IL-21. Each member of this family has a four alpha helix bundle. IL-2 signals through the IL-2 receptor, a complex consisting of tree subunits, termed alpha, beta and gamma. The IL-2 R gamma is shared by cytokine receptors of all members of cytokine family. Mature mouse IL-2 shares 56% and 73% aa sequence identity with human and rat IL-2, respectively. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma ? T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.Thus, IL-2 may be a key cytokine in the natural suppression of autoimmunity.
| Product Name: | Mouse Interleukin-2/IL-2 Recombinant Protein (RPES1396) |
| Product Code: | RPES1396 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | E.coli |
| Synonyms: | IL2, Aldesleukin, Interleukin 2, Interleukin-2, IL-2, IL2, T-cell growth facter, T cell growth factor, TCGF |
| Accession: | P04351 |
| Sequence: | Ala21-Gln169 |
| Activity: | Measured in a cell proliferation assay using CTLL?2 mouse cytotoxic T cells. The specific activity of Recombinant Human IL-2 is ?1×107 IU/mg. |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse Interleukin-2 is produced by our E.coli expression system and the target gene encoding Ala21-Gln169 is expressed. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 17.4 kDa |
| AP Mol Mass: | 17 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM Sodium Citrate, 0.2%Tween 80,pH3.0. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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