Immunology Recombinant Proteins
Mouse IL1R1/CD121a Recombinant Protein (RPES1157)
- SKU:
- RPES1157
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Research Area:
- Immunology
Description
Mouse IL1R1/CD121a Recombinant Protein
Mouse Interleukin-1 receptor type 1/IL-1 RI is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein is a receptor for interleukin 1 alpha (IL1A), interleukin 1 beta (IL1B), and interleukin 1 receptor antagonist (IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. An IL1 receptor accessory protein that can heterodimerize with the Type I receptor in the presence of IL1? or IL1βbut not IL1ra, was identified. This Type I receptor complex appears to mediate all the known IL1 biological responses. The receptor Type II has a short cytoplasmic domain and does not transduce IL1 signals. In addition to the membranebound form of IL1 RII, a naturallyoccurring soluble form of IL1 RII has been described. It has been suggested that the Type II receptor, either as the membranebound or as the soluble form, serves as a decoy for IL1 and inhibits IL1 action by blocking the binding of IL1 to the signaling Type I receptor complex.
| Product Name: | Mouse IL1R1/CD121a Recombinant Protein (RPES1157) |
| Product Code: | RPES1157 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | Human Cells |
| Synonyms: | Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha, IL-1R-alpha, p80, CD121a, mIL-1R1 |
| Accession: | P13504 |
| Sequence: | Leu20-Lys338 |
| Fusion tag: | C-Fc |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse Interleukin-1 receptor type 1 is produced by our Mammalian expression system and the target gene encoding Leu20-Lys338 is expressed with a Fc tag at the C-terminus. |
| Purity: | > 90 % as determined by SDS-PAGE |
| Mol Mass: | 64.0 kDa |
| AP Mol Mass: | 85-110&140 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Related Products
Mouse IL1R1/CD121a Recombinant Protein (RPES1533)
Immunology Recombinant Proteins
Mouse IL1R1/CD121a Recombinant Protein (RPES4395)
Immunology Recombinant Proteins
Mouse IL1R1/CD121a Recombinant Protein (RPES1644)
Immunology Recombinant Proteins
