Immunology Recombinant Proteins
Mouse IL beta/IL1B Recombinant Protein (RPES1726)
- SKU:
- RPES1726
Description
Mouse IL beta/IL1B Recombinant Protein
Interleukin-1 (IL-1) designates two proteins, IL-1? and IL-1β, which are the products of distinct genes, but recognize the same cell surface receptors. IL-1? and IL-1β are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins. The proteins are synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17.5 kDa. The specific protease responsible for the processing of IL-1β, designated interleukin 1β-converting enzyme (ICE), has been described. Mature human and mouse IL-1β share approximately 75% amino acid sequence identity and human IL-1β has been found to be active on murine cell lines.
| Product Name: | Mouse IL beta/IL1B Recombinant Protein (RPES1726) |
| Product Code: | RPES1726 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | E.coli |
| Synonyms: | Interleukin-1 Beta, IL-1 Beta, Il1b |
| Accession: | P10749 |
| Sequence: | Val118-Ser269 |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse Interleukin-1 beta is produced by our E.coli expression system and the target gene encoding Val118-Ser269 is expressed. |
| Purity: | > 95 % as determined by SDS-PAGE |
| Mol Mass: | 17.4 kDa |
| AP Mol Mass: | 16 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 50mM TrisHCl, 50mM NaCl, pH 8.0. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Mouse |
Research Area: |
Immunology |
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