Mouse IgG Recombinant Protein (RPPB3749)

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SKU:
RPPB3749
Product Type:
Recombinant Protein
Species:
Mouse
Uniprot:
P01863

Description

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Product Name:Mouse IgG Recombinant Protein
Product Code:RPPB3749
Size:20µg
Species:Mouse
Target:IgG
Synonyms:Ig gamma-2A chain C region, A allele, Immunoglobulin heavy chain gamma polypeptide, Ighg, Igh-1, Igh-1a, 1810060O09Rik.
Source:Hi-5 cells
Physical Appearance:Sterile Filtered colorless solution.
Formulation:IgG protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0) and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:ADPEPRGPTI KPCPPCKCPA PNLLGGPSVF IFPPKIKDVL MISLSPIVTC VVVDVSEDDP DVQISWFVNN VEVHTAQTQT HREDYNSTLR VVSALPIQHQ DWMSGKEFKC KVNNKDLPAP IERTISKPKG SVRAPQVYVL PPPEEEMTKK QVTLTCMVTD FMPEDIYVEW TNNGKTELNY KNTEPVLDSD GSYFMYSKLR VEKKNWVERN SYSCSVVHEG LHNHHTTKSF SRTPGKHHHH HH

Immunoglobulin G (IgG)�are antibody molecules. Each IgG is composed of four peptide chains�- 2 heavy chains�g and 2 light chains. Also, each IgG has 2 antigen binding sites. IgG antibodies are involved in primarily the secondary immune response. The presence of specific IgG, generally, relates to maturation of the antibody response. IgG also has an imperative role in Antibody-dependent cell-mediated cytotoxicity (ADCC) and Intracellular antibody-mediated proteolysis, in which it binds to TRIM21 (the receptor with greatest affinity to IgG in humans) in order to direct marked virions to the proteasome in the cytosol.

IgG Mouse Recombinant produced in Hi-5 cells is a single polypeptide chain containing 242 amino acids (98-330 a.a) and having a molecular mass of 27.5kDa.IgG is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.

UniProt Code:P01863
NCBI GenInfo Identifier:121048
NCBI Gene ID:380793
NCBI Accession:P01863.1
UniProt Related Accession:P01863,P01864,P01865,P84751
Molecular Weight:36,389 Da
NCBI Full Name:Ig gamma-2A chain C region, A allele
NCBI Synonym Full Names:immunoglobulin heavy constant gamma 2A
NCBI Official Symbol:Ighg2a��
NCBI Official Synonym Symbols:Igh-1; Igh-1a; 1810060O09Rik��
UniProt Protein Name:Ig gamma-2A chain C region, A allele
UniProt Synonym Protein Names:Immunoglobulin heavy chain gamma polypeptide
UniProt Gene Name:Ighg��
UniProt Entry Name:GCAA_MOUSE
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