Mouse/Human CD44 Monoclonal Antibody [IM7](AGEL0364)

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SKU:
AGEL0364
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Host Species:
Rat
Isotype:
IgG2b
Clone:
IM7
Conjugation:
Unconjugated
Applications:
FC
Applications:
IHC
Applications:
IP

Description

system_update_altDatasheet
Antibody Name:Mouse/Human CD44 Monoclonal Antibody
Antibody Code:AGEL0364
Size:100µg
Clone:IM7
Synonyms:CD44 antigen, CD44, CDw44, Epican, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I, CD44, LHR, MDU2, MDU3, MIC4
Host Species:Rat
Species Reactivity:Mouse, Human
Applications:FC, IHC, IP
Concentration:1mg/mL
Isotype: IgG2b
Conjugation:Unconjugated
Applications:FC, IHC, IP
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:PBS with 0.05% Proclin300
Storage:Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Gene ID:12505960
Uniprot:P15379, P16070
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.
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