Mouse/Human CD11b Monoclonal Antibody (PE Conjugated) [M1/70](AGEL0307)

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SKU:
AGEL0307
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Host Species:
Rat
Isotype:
IgG2b
Clone:
M1/70
Conjugation:
PE
Applications:
FC

Description

system_update_altDatasheet
Antibody Name:Mouse/Human CD11b Monoclonal Antibody (PE Conjugated)
Antibody Code:AGEL0307
Size:200 Tests
Clone:M1/70
Synonyms:Integrin alpha-M, Itgam, CD11 antigen-like family member B, CR-3 alpha chain, Leukocyte adhesion receptor MO1, CD11b
Host Species:Rat
Species Reactivity:Mouse, Human
Applications:FC
Concentration:5uL
Isotype:IgG2b
Conjugation:PE
Applications:FC
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:PBS with 0.05% Proclin300, 1% BSA
Storage:Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Gene ID:164093684
Uniprot:P05555, P11215
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
Mouse CD19 Monoclonal Antibody (FITC Conjugated)Mouse bone marrow cells are stained with Anti-Mouse/Human CD11b Monoclonal Antibody(PE Conjugated)(filled gray curve). Unstained bone marrow cells (blank black curve) are used as control.
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