Description
system_update_altDatasheet
Antibody Name: | Mouse/Human CD11b Monoclonal Antibody (FITC Conjugated) |
Antibody Code: | AGEL0306 |
Size: | 200 Tests |
Clone: | M1/70 |
Synonyms: | Integrin alpha-M, Itgam, CD11 antigen-like family member B, CR-3 alpha chain, Leukocyte adhesion receptor MO1, CD11b |
Host Species: | Rat |
Species Reactivity: | Mouse, Human |
Applications: | FC |
Concentration: | 5uL |
Isotype: | IgG2b |
Conjugation: | FITC |
Applications: | FC |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Gene ID: | 164093684 |
Uniprot: | P05555, P11215 |
Background: | CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen. |
Mouse bone marrow cells are stained with Anti-Mouse/Human CD11b Monoclonal Antibody(FITC Conjugated)(filled gray curve). Unstained bone marrow cells (blank black curve) are used as control. |