Description
Antibody Name: | Mouse/Human CD11b Monoclonal Antibody (AF647 Conjugated) |
Antibody Code: | AGEL1113 |
Size: | 50µg |
Clone: | M1/70 |
Synonyms: | Integrin alpha-M,Itgam,CD11 antigen-like family member B,CR-3 alpha chain,Leukocyte adhesion receptor MO1,CD11b |
Host Species: | Rat |
Species Reactivity: | Human, Mouse |
Applications: | FC |
Concentration: | 1mg/mL |
Isotype: | IgG2a,k |
Conjugation: | AF647 |
Applications: | FC |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. |
Gene ID: | 16409,3684 |
Uniprot: | P05555, P11215 |
Background: | CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen. |
C57BL/6 murine bone marrow cells are stained with Anrti-Mouse/Human CD11b Monoclonal Antibody(AF647 Conjuaged)[Used at ?g/106 cells dilution](filled gray histogram). Unstained bone marrow cells (empty black histogram) are used as control. |