Growth Factors & Cytokines Recombinant Proteins

Mouse HGF Recombinant Protein (RPES1630)

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SKU:
RPES1630
Product Type:
Recombinant Protein
Species:
Mouse
Research Area:
Growth Factors & Cytokines

Description

system_update_altDatasheet

Mouse HGF Recombinant Protein

HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases. Mouse HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. It is cleaved after the fourth Kringle domain by a serine protease to form bioactive disulfide-linked HGF with a 60 kDa alpha and 30 kDa beta chain. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis. It can also alter epithelium morphology by the induction of nectin-1 alpha ectodomain shedding, an adhesion protein component of adherens junctions.

Product Name:Mouse HGF Recombinant Protein (RPES1630)
Product Code:RPES1630
Size:10µg
Species:Mouse
Expressed Host:Human Cells
Synonyms:Hepatopoietin-A, Scatter factor, SF, Deafnes, Autosomal recessive 39, DFNB39,F-TCF, Hepatocyte growth factor
Accession:Q08048
Sequence:Gln33-Leu728
Fusion tag:C-His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Mouse HGF is produced by our Mammalian expression system and the target gene encoding Gln33-Leu728 is expressed with a 6His tag at the C-terminus.
Purity:> 95% as determined by reducing SDS-PAGE.
Mol Mass:80.4 kDa
AP Mol Mass:80-100 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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