Mouse HAVCR1 Recombinant Protein (RPPB5500)
- SKU:
- RPPB5500
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Uniprot:
- Q5QNS5
Description
| Product Name: | Mouse HAVCR1 Recombinant Protein |
| Product Code: | RPPB5500 |
| Size: | 10µg |
| Species: | Mouse |
| Target: | HAVCR1 |
| Synonyms: | Hepatitis A virus cellular receptor 1 homolog, HAVcr-1,Kidney injury molecule 1, KIM-1, T cell immunoglobulin and mucindomain-containing protein 1, TIMD-1, T cell membrane protein 1, T-cellimmunoglobulin mucin receptor 1, TIM-1. |
| Source: | Sf9 Insect cells |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | HAVCR1 protein solution (0.25mg/ml) contains PhosphateBuffered Saline (pH 7.4) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).�Avoid multiple freeze-thaw cycles. |
| Purity: | Greaterthan 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | YVEVKGVVGH PVTLPCTYST YRGITTTCWG RGQCPSSACQ NTLIWTNGHRVTYQKSSRYN LKGHISEGDV SLTIENSVES DSGLYCCRVE IPGWFNDQKV TFSLQVKPEI PTRPPTRPTTTRPTATGRPT TISTRSTHVP TSIRVSTSTP PTSTHTWTHK PEPTTFCPHE TTAEVTGIPS HTPTDWNGTVTSSGDTWSNH TEAIPPGKPQ KNPTKGHHHH HH |
Hepatitis A virus cellular receptor 1 (HAVCR1) is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. HAVCR1 is a type I trans-membrane structural glycoprotein located in the renal proximal tubule epithelial cells. HAVCR1 protein may be involved in the control of asthma and allergic diseases. The reference genome represents an allele which retains a MTTVP amino acid segment that presents defense against atopy in HHAV seropositive individuals.
HAVCR1 produced in Sf9 Baculovirus cells is a single,glycosylated polypeptide chain containing 222 amino acids (22-237 a.a.) andhaving a molecular mass of 24.4kDa (Migrates at 40-57kDa on SDS-PAGE underreducing conditions).�HAVCR1 is expressed with a 6 amino acid His tag atC-Terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | TIM-1: May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair. Belongs to the immunoglobulin superfamily. TIM family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 11|11 B1.1 Cellular Component: cell surface; integral component of membrane; membrane Molecular Function:phosphatidylserine binding; protein binding Biological Process: positive regulation of mast cell activation |
| UniProt Code: | Q5QNS5 |
| NCBI GenInfo Identifier: | 262231823 |
| NCBI Gene ID: | 171283 |
| NCBI Accession: | NP_001160103.1 |
| UniProt Secondary Accession: | Q5QNS5,Q7TPU2, Q8VIM1, Q8VIM2, |
| UniProt Related Accession: | Q5QNS5 |
| Molecular Weight: | |
| NCBI Full Name: | hepatitis A virus cellular receptor 1 homolog isoform b |
| NCBI Synonym Full Names: | hepatitis A virus cellular receptor 1 |
| NCBI Official Symbol: | Havcr1�� |
| NCBI Official Synonym Symbols: | Tim1; KIM-1; TIM-1; Timd1; AI503787�� |
| NCBI Protein Information: | hepatitis A virus cellular receptor 1 homolog |
| UniProt Protein Name: | Hepatitis A virus cellular receptor 1 homolog |
| UniProt Synonym Protein Names: | Kidney injury molecule 1; KIM-1; T cell immunoglobulin and mucin domain-containing protein 1; TIMD-1; T cell membrane protein 1; T-cell immunoglobulin mucin receptor 1; TIM-1 |
| UniProt Gene Name: | Havcr1�� |
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