Chemokines Recombinant Proteins

Mouse GRO g Recombinant Protein (RPPB1154)

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SKU:
RPPB1154
Product Type:
Recombinant Protein
Species:
Mouse
Uniprot:
Q6W5C0
Research Area:
Chemokines

Description

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Product Name:Mouse GRO g Recombinant Protein
Product Code:RPPB1154
Size:10µg
Species:Mouse
Target:GRO g
Synonyms:C-X-C motif chemokine 3, Dendritic cell inflammatory protein 1, Cxcl3, Dcip1, Gm1960, GRO-g.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:GRO-gamma protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 50% glycerol, 0.15M NaCl and 5mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMAVVAS ELRCQCLNTL PRVDFETIQS LTVTPPGPHC TQTEVIATLK DGQEVCLNPQ GPRLQIIIKK ILKSGKSS

Chemokine (C-X-C motif) ligand 3 (CXCL3) is a small cytokine belonging to the CXC chemokine family that is also known as GRO3 oncogene (GRO3), GRO protein gamma (GROg) and macrophage inflammatory protein-2-beta (MIP2b). CXCL3 controls migration and adhesion of monocytes and mediates it effects on its target cell by interacting with a cell surface chemokine receptor called CXCR2. The gene for CXCL3 is located on chromosome 4 in a cluster of other CXC chemokines.

GRO-g Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 98 amino acids (28-100 a.a.) and having a molecular mass of 10.6kDa.CXCL3 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion.
UniProt Protein Details:
NCBI Summary:This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. [provided by RefSeq, May 2013]
UniProt Code:Q6W5C0
NCBI GenInfo Identifier:42600573
NCBI Gene ID:330122
NCBI Accession:NP_976065.1
UniProt Secondary Accession:Q6W5C0,Q3UNK9
UniProt Related Accession:Q6W5C0
Molecular Weight:10,686 Da
NCBI Full Name:C-X-C motif chemokine 3
NCBI Synonym Full Names:chemokine (C-X-C motif) ligand 3
NCBI Official Symbol:Cxcl3��
NCBI Official Synonym Symbols:Dcip1; Gm1960��
NCBI Protein Information:C-X-C motif chemokine 3
UniProt Protein Name:C-X-C motif chemokine 3
UniProt Synonym Protein Names:Dendritic cell inflammatory protein 1
Protein Family:
UniProt Gene Name:Cxcl3��
UniProt Entry Name:
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