Proteases Recombinant Proteins

Mouse Granzyme B(G,H)/GZMB Recombinant Protein (RPES0956)

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SKU:
RPES0956
Product Type:
Recombinant Protein
Species:
Mouse
Research Area:
Proteases

Description

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Mouse Granzyme B(G,H)/GZMB Recombinant Protein

Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Product Name:Mouse Granzyme B(G,H)/GZMB Recombinant Protein (RPES0956)
Product Code:RPES0956
Size:10µg
Species:Mouse
Expressed Host:Human Cells
Synonyms:Granzyme B(G,H),CTLA-1,Cytotoxic cell protease 1,CCP1,Fragmentin-2,Gzmb,Ctla-1, Ctla1
Accession:P04187
Sequence:Gly19-Ser247
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Mouse Granzyme B is produced by our Mammalian expression system and the target gene encoding Gly19-Ser247 is expressed with a 6His tag at the C-terminus.
Purity:> 85 % as determined by SDS-PAGE
Mol Mass:26.5 kDa
AP Mol Mass:35kDa
Formulation:Supplied as a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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