Enzymes Recombinant Proteins

Mouse GOT2 Recombinant Protein (RPPB1728)

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SKU:
RPPB1728
Product Type:
Recombinant Protein
Species:
Mouse
Uniprot:
P05202
Research Area:
Enzymes

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Mouse GOT2 Recombinant Protein
Product Code:RPPB1728
Size:10µg
Species:Mouse
Target:GOT2
Synonyms:Transaminase A, KAT4, KATIV, KAT-4, KAT-IV, Kynurenine Aminotransferase 4.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The GOT2 solution (0.5 mg/ml) contains 10% Glycerol and Phosphate Buffered Saline (pH7.4)
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than�90.0%�as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MSSWWTHVEM GPPDPILGVT EAFKRDTNSK KMNLGVGAYRDDNGKPYVLP SVRKAEAQIA AKNLDKEYLP IGGLAEFCKA SAELALGENN EVLKSGRFVTVQTISGTGAL RVGASFLQRF FKFSRDVFLP KPSWGNHTPI FRDAGMQLQG YRYYDPKTCGFDFSGALEDI SKIPEQSVLL LHACAHNPTG VDPRPEQWKE IASVVKKKNL FAFFDMAYQGFASGDGDKDA WAVRHFIEQG INVCLCQSYA KNMGLYGERV GAFTVVCKDA EEAKRVESQLKILIRPLYSN PPLNGARIAA TILTSPDLRK QWLQEVKGMA DRIISMRTQL VSNLKKEGSSHNWQHITDQI GMFCFTGLKP EQVERLTKEF SVYMTKDGRI SVAGVTSGNV GYLAHAIHQV TK
Biological Activity:Specific activity is > 20 units/mg. Measured by the amount of enzyme that converts 1umole of alpha-ketoglutarate to L-Glutamate per minute at pH 8.0 at 25C?.

GOT2 is a pyridoxal phosphate-dependent enzyme which is found in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2. GOT2 participates in amino acid metabolism and the urea and tricarboxylic acid cycles. Both enzymes are homodimeric and demonstrate close homology.

GOT2 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 422 amino acids (30-430 aa) and having a molecular mass of 46.8kDa.GOT2 is fused to a 21 amino acid His tag at N-terminus and purified by proprietary chromatographic techniques.

UniProt Protein Function:Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids.
UniProt Code:P05202
NCBI GenInfo Identifier:6754036
NCBI Gene ID:14719
NCBI Accession:NP_034455.1
UniProt Secondary Accession:P05202,O09188, Q3TIP6, Q3UD91, Q5HZH5,
UniProt Related Accession:P05202
Molecular Weight:47,411 Da
NCBI Full Name:aspartate aminotransferase, mitochondrial
NCBI Synonym Full Names:glutamatic-oxaloacetic transaminase 2, mitochondrial
NCBI Official Symbol:Got2��
NCBI Official Synonym Symbols:Got-2; Kyat4; mAspAT; FABP-pm; AL022787��
NCBI Protein Information:aspartate aminotransferase, mitochondrial
UniProt Protein Name:Aspartate aminotransferase, mitochondrial
UniProt Synonym Protein Names:Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Plasma membrane-associated fatty acid-binding protein; FABPpm; Transaminase A
Protein Family:Protein
UniProt Gene Name:Got2��
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