Enzymes Recombinant Proteins

Mouse GOT2 Recombinant Protein (RPPB1727)

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SKU:
RPPB1727
Product Type:
Recombinant Protein
Species:
Mouse
Uniprot:
P00505
Research Area:
Enzymes

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Mouse GOT2 Recombinant Protein
Product Code:RPPB1727
Size:10µg
Species:Mouse
Target:GOT2
Synonyms:Transaminase A, KAT4, KATIV, KAT-4, KAT-IV,Kynurenine Aminotransferase 4.
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless solution.
Formulation:The GOT2 solution (0.5mg/ml) contains PBS, pH 7.4 and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MSSWWTHVEM GPPDPILGVT EAFKRDTNSK KMNLGVGAYR DDNGKPYVLP SVRKAEAQIA AKNLDKEYLP IGGLAEFCKA SAELALGENN EVLKSGRFVT VQTISGTGAL RVGASFLQRF FKFSRDVFLP KPSWGNHTPI FRDAGMQLQG YRYYDPKTCG FDFSGALEDI SKIPEQSVLL LHACAHNPTG VDPRPEQWKE IASVVKKKNL FAFFDMAYQG FASGDGDKDA WAVRHFIEQG INVCLCQSYA KNMGLYGERV GAFTVVCKDA EEAKRVESQL KILIRPLYSN PPLNGARIAA TILTSPDLRK QWLQEVKGMA DRIISMRTQL VSNLKKEGSS HNWQHITDQI GMFCFTGLKP EQVERLTKEF SVYMTKDGRI SVAGVTSGNV GYLAHAIHQV
Biological Activity:Activity is greater than 20 units/mg, and is defined as the amount of enzyme that converts 1umole of alpha-ketoglutarate to L-Glutamate per minute at pH 8.0 at 25?.

GOT2 is a pyridoxal phosphate-dependent enzyme which is found in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2. GOT2 takes part in amino acid metabolism and the urea and tricarboxylic acid cycles. Both enzymes are homodimeric and demonstrate close homology.

GOT2 Recombinant Mouse produced in E.Coli is a single, non-glycosylated polypeptide chain containing 424 amino acids (30-430 a.a.) and having a molecular mass of 46.8kDa. Mouse GOT2 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Code:P00505
NCBI GenInfo Identifier:73486658
NCBI Gene ID:2806
NCBI Accession:NP_002071.2
UniProt Secondary Accession:P00505,Q53FL3, Q9BWA3,
UniProt Related Accession:P00505
Molecular Weight:430
NCBI Full Name:aspartate aminotransferase, mitochondrial
NCBI Synonym Full Names:glutamic-oxaloacetic transaminase 2, mitochondrial
NCBI Official Symbol:GOT2��
NCBI Official Synonym Symbols:KAT4; KATIV; mitAAT��
NCBI Protein Information:aspartate aminotransferase, mitochondrial; FABP-1; FABPpm; mAspAT; transaminase A; aspartate transaminase 2; fatty acid-binding protein; aspartate aminotransferase 2; kynurenine aminotransferase 4; kynurenine aminotransferase IV; glutamate oxaloacetate tr
UniProt Protein Name:Aspartate aminotransferase, mitochondrial
UniProt Synonym Protein Names:Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Plasma membrane-associated fatty acid-binding protein; FABPpm; Transaminase A
UniProt Gene Name:GOT2��
UniProt Entry Name:AATM_HUMAN
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