Growth Factors & Cytokines Recombinant Proteins
Mouse GM-CSF/CSF2 Recombinant Protein (RPES0902)
- SKU:
- RPES0902
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Research Area:
- Growth Factors & Cytokines
Description
Mouse GM-CSF/CSF2 Recombinant Protein
Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factorthat can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by anumber of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cellsand fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophageprogenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. Onmature hematopoietic, monocytes/ macrophages and eosinophils. GM-CSF has a functional role on nonhematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF canalso stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma andadenocarcinoma cell lines.
| Product Name: | Mouse GM-CSF/CSF2 Recombinant Protein (RPES0902) |
| Product Code: | RPES0902 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | E.coli |
| Synonyms: | Granulocyte-macrophage colony-stimulating factor,Csf2,GM-CSF,Colony-stimulating factor,Csfgm |
| Accession: | P01587 |
| Sequence: | Ala18-Lys141 |
| Activity: | Measured in a cell proliferation assay using PDC-P1 cells The ED50 for this effect is 15-50 pg/ml. |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse Granulocyte-Macrophage Colony-Stimulating Factor is produced by our E.coli expression system and the target gene encoding Ala18-Lys141 is expressed. |
| Purity: | > 95 % as determined by SDS-PAGE |
| Mol Mass: | 14.2 kDa |
| AP Mol Mass: | 15 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl, pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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