Frizzled homolog 1 (FZD1), also known as Frizzled-1, a member of the G-protein-coupled receptor superfamily, mediates Wnt signaling by serving as a co-receptor with LRP-5 for Wnt ligands. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif.
Product Name:
Mouse Frizzled 1/FZD1 Recombinant Protein (RPES0829)
Product Code:
RPES0829
Size:
10µg
Species:
Mouse
Expressed Host:
Human Cells
Synonyms:
Frizzled-1, Fz-1, mFz1, Fzd1, Frizzled homolog 1
Accession:
O70421
Sequence:
Val69-His248
Fusion tag:
C-Fc
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Mouse Frizzled (Drosophila) Homolog 1 is produced by our Mammalian expression system and the target gene encoding Val69-His248 is expressed with a Fc tag at the C-terminus.
Purity:
> 95 % as determined by SDS-PAGE
Mol Mass:
46.8 kDa
AP Mol Mass:
35-40 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
