Enzymes Recombinant Proteins

Mouse FOLH1 Recombinant Protein (RPPB1648)

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SKU:
RPPB1648
Product Type:
Recombinant Protein
Species:
Mouse
Uniprot:
O35409
Research Area:
Enzymes

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Mouse FOLH1 Recombinant Protein
Product Code:RPPB1648
Size:10µg
Species:Mouse
Target:FOLH1
Synonyms:Folh1, GCP2, mopsm, Glutamate carboxypeptidase 2, Folatehydrolase 1, Folylpoly-gamma-glutamate carboxypeptidase, FGCP, Glutamatecarboxypeptidase II, GCPII, Naalad1.
Source:Sf9 Insect cells
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The FOLH1 solution (0.5mg/ml) contains Phosphate BufferedSaline (pH 7.4) and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity:Greater than 85% as determined by SDS-PAGE.
Amino Acid Sequence:ADPKPSNEAT GNVSHSGMKK EFLHELKAEN IKKFLYNFTR TPHLAGTQNNFELAKQIHDQ WKEFGLDLVE LSHYDVLLSY PNKTHPNYIS IINEDGNEIF KTSLSEQPPP GYENISDVVPPYSAFSPQGT PEGDLVYVNY ARTEDFFKLE REMKISCSGK IVIARYGKVF RGNMVKNAQL AGAKGMILYSDPADYFVPAV KSYPDGWNLP GGGVQRGNVL NLNGAGDPLT PGYPANEHAY RHELTNAVGL PSIPVHPIGYDDAQKLLEHM GGPAPPDSSW KGGLKVPYNV GPGFAGNFST QKVKMHIHSY TKVTRIYNVI GTLKGALEPDRYVILGGHRD AWVFGGIDPQ SGAAVVHEIV RSFGTLKKKG RRPRRTILFA SWDAEEFGLL GSTEWAEEHSRLLQERGVAY INADSSIEGN YTLRVDCTPL MYSLVYNLTK ELQSPDEGFE GKSLYDSWKE KSPSPEFIGMPRISKLGSGN DFEVFFQRLG IASGRARYTK NWKTNKVSSY PLYHSVYETY ELVVKFYDPT FKYHLTVAQVRGAMVFELAN SIVLPFDCQS YAVALKKYAD TIYNISMKHP QEMKAYMISF DSLFSAVNNFTDVASKFNQR LQELDKSNPI LLRIMNDQLM YLERAFIDPLGLPGRPFYRH IIYAPSSHNK YAGESFPGIY DALFDISSKV NASKAWNEVK RQISIATFTV QAAAETLREV AHHHHHH
UniProt Code:O35409

Folate Hydrolase 1 (Folh1) is asingle pass type 2 membrane protein which is expressed mainly in prostate epithelium.Folh1 which is a part of the peptidase M28 family and M28B subfamily has bothfolate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase activity. Folh1can be found in urinary bladder, kidney, testis, ovary, stomach, smallintestine colon, and the capillary endothelium of various tumors. Therefore, Folh1plays a role in directed imaging and therapy of recurrent of metastaticdisease.

FOLH1 Mouse Recombinant produced in in Sf9 Baculoviruscells is a single, non-glycosylated polypeptide chain containing 717 aminoacids (45-752a.a) and having a molecular mass of 80.5kDa (Migrates at 70-100kDaon SDS-PAGE under reducing conditions). FOLH1 is fused to a 6 amino acid His-tag at C-Terminusand purified by proprietary chromatographic techniques.

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