Immunology Recombinant Proteins
Mouse Factor D Recombinant Protein (RPES5151)
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- SKU:
- RPES5151
Description
system_update_altDatasheet
Mouse Factor D Recombinant Protein
Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for cleavage of the complement protein C3, which leads to the activation of terminal complement component C5-9 to form the membrane attack complex on microbial or cellular surfaces. It also functions in the regulation of systemic energy balance and physiologic and pathologic processes, including immunity and inflammation.
| Product Name: | Mouse Factor D Recombinant Protein (RPES5151) |
| Product Code: | RPES5151 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | Human Cells |
| Synonyms: | Complement factor D, 28 kDa adipocyte protein, Adipsin, C3 convertase activator, Properdin factor D, Cfd, Adn, Df |
| Accession: | P03953 |
| Sequence: | Ile26-Ser259 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse Complement factor D is produced by our Mammalian expression system and the target gene encoding Ile26-Ser259 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by SDS-PAGE |
| Mol Mass: | 26.5 kDa |
| AP Mol Mass: | 40-49 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mMTris,150mMNaCl,pH7.5. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Mouse |
Research Area: |
Immunology |
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