Chemokines Recombinant Proteins
Mouse Exodus-2 Recombinant Protein (RPPB1133)
- SKU:
- RPPB1133
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Uniprot:
- P84444
- Research Area:
- Chemokines
Description
| Product Name: | Mouse Exodus-2 Recombinant Protein |
| Product Code: | RPPB1133 |
| Size: | 10µg |
| Species: | Mouse |
| Target: | Exodus-2 |
| Synonyms: | Ccl21a, C-C motif chemokine 21a, 6Ckine, Beta-chemokine exodus-2, Small-inducible cytokine A21a,Thymus-derived chemotactic agent 4, TCA4, Ccl21a, Scya21, Scya21a, 6CKBAC2, 6Ckine, ALP,AW987545, CKb9, plt, Scya21b, SLC. |
| Source: | Sf9 Insect cells |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The� Exodus-2 solution (0.5mg/ml) contains� Phosphate-Buffered Saline (pH 7.4) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than�90.0%�as determined by SDS-PAGE. |
| Amino Acid Sequence: | ADPSDGGGQD CCLKYSQKKI PYSIVRGYRK QEPSLGCPIP AILFSPRKHS KPELCANPEE GWVQNLMRRL DQPPAPGKQS PGCRKNRGTS KSGKKGKGSK GCKRTEQTQP SRGHHHHHH |
Exodus-2 protein or CCL21 is a cytokine, part of the CC chemokines subgroup. Because of its 6 conserved residues of the cysteine amino acid (instead of the 4 residues we usually see in chemokines), the protein is also named 6Ckine and SLC (secondary lymphoid-tissue chemokine). The gene that codes for this protein is located on chromosome 9 in humans. The Exodus-2 is binding to the CCR7 receptor, which is a chemokine receptor located to the cell�s surface.
Exodus-2 Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 119 amino acids (24-133aa) and having a molecular mass of 13.1kDa.Exodus-2 is fused to a 9 amino acid His tag at C-terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Potent mesangial cell chemoattractant. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P84444 |
| NCBI GenInfo Identifier: | 302488378 |
| NCBI Gene ID: | 100504362 |
| NCBI Accession: | NP_001180596.1 |
| UniProt Secondary Accession: | P84444,O09002, O09006, Q3U1J2, Q91V84 |
| UniProt Related Accession: | P84444 |
| Molecular Weight: | 14,558 Da |
| NCBI Full Name: | predicted gene 1987 |
| NCBI Synonym Full Names: | predicted gene 1987 |
| NCBI Official Symbol: | Gm1987�� |
| NCBI Official Synonym Symbols: | 100038965�� |
| NCBI Protein Information: | predicted gene 1987 |
| UniProt Protein Name: | C-C motif chemokine 21a |
| UniProt Synonym Protein Names: | 6Ckine; Beta-chemokine exodus-2; Small-inducible cytokine A21a; Thymus-derived chemotactic agent 4; TCA4 |
| Protein Family: | |
| UniProt Gene Name: | Ccl21a�� |
| UniProt Entry Name: |
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