Mouse CLEC10A/CD301 Recombinant Protein (RPES5241)
- SKU:
- RPES5241
- Product Type:
- Recombinant Protein
- Species:
- Mouse
Description
Mouse CLEC10A/CD301 Recombinant Protein
CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs; CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is a type II transmembrane glycoproteins and is expressed on macrophages and related cells of myeloid origins, particularly immature dendritic cells (DCs). There are 2 homologues: MGL1 and MGL2 (CD301a and CD301b) in mice. MGL1/CD301a induces both the production and secretion of interleukin (IL)-10. MGL1/CD301a plays a protective role against colitis by effectively inducing IL-10 production by colonic lamina propria macrophages in response to invading commensal bacteria.
| Product Name: | Mouse CLEC10A/CD301 Recombinant Protein (RPES5241) |
| Product Code: | RPES5241 |
| Size: | 50µg |
| Species: | Mouse |
| Expressed Host: | HEK293 Cells |
| Synonyms: | CD301a,M-ASGP-BP-1,Mgl,Mgl1 |
| Accession: | NP_001191181.1 |
| Sequence: | Gln 58-Ser 305 |
| Fusion tag: | N-His |
| Endotoxin: | <1.0 EU per µg of the protein as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the extracellular domain of mouse CLEC10A (NP_001191181.1) (Gln 58-Ser 305) was fused with a polyhistidine tag at the N-terminus. |
| Purity: | > 97 % as determined by SDS-PAGE |
| Mol Mass: | 30.7 kDa |
| AP Mol Mass: | 37 kDa |
| Formulation: | Lyophilized from sterile PBS, pH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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