Mouse CD8a Monoclonal Antibody (Biotin Conjugated) [53.6.7](AGEL0379)
(No reviews yet)
Write a Review
](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/11207/15261/mouse-cd8a-monoclonal-antibody-biotin-conjugated-53.6.7agel0379__33284__41793.1706269400.jpg?c=1 "Mouse CD8a Monoclonal Antibody (Biotin Conjugated) [53.6.7](AGEL0379)")
- SKU:
- AGEL0379
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rat
- Isotype:
- IgG2a
- Clone:
- 53.6.7
- Conjugation:
- Biotin
- Applications:
- FC
](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/11207/15261/mouse-cd8a-monoclonal-antibody-biotin-conjugated-53.6.7agel0379__33284__41793.1706269400.jpg?c=1&imbypass=on "Mouse CD8a Monoclonal Antibody (Biotin Conjugated) [53.6.7](AGEL0379)")
Description
system_update_altDatasheet
| Antibody Name: | Mouse CD8a Monoclonal Antibody (Biotin Conjugated) |
| Antibody Code: | AGEL0379 |
| Size: | 100µg |
| Clone: | 53.6.7 |
| Synonyms: | T-cell surface glycoprotein CD8 alpha chain, CD8A, T-lymphocyte differentiation antigen T8/Leu-2, MAL |
| Host Species: | Rat |
| Species Reactivity: | Mouse |
| Applications: | FC |
| Concentration: | 1mg/mL |
| Isotype: | IgG2a |
| Conjugation: | Biotin |
| Applications: | FC |
| Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Storage: | Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Gene ID: | 12525 |
| Uniprot: | P01731 |
| Background: | CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck. |
Related Products
](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/590x590/products/11208/15262/mouse-cd8a-monoclonal-antibody-fitc-conjugated-53.6.7agel0380__00486__26705.1706269401.jpg?c=1 "Mouse CD8a Monoclonal Antibody (FITC Conjugated) [53.6.7](AGEL0380)")
Mouse CD8a Monoclonal Antibody (FITC Conjugated) [53.6.7](AGEL0380)
system_update_altDatasheetOverviewAnti
](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/590x590/products/11209/15263/mouse-cd8a-monoclonal-antibody-pe-conjugated-53.6.7agel0381__15997__15864.1706269401.jpg?c=1 "Mouse CD8a Monoclonal Antibody (PE Conjugated) [53.6.7](AGEL0381)")
Mouse CD8a Monoclonal Antibody (PE Conjugated) [53.6.7](AGEL0381)
system_update_altDatasheetOverviewAnti
](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/590x590/products/11210/15264/mouse-cd8a-monoclonal-antibody-apc-conjugated-53.6.7agel0382__47697__66887.1706269401.jpg?c=1 "Mouse CD8a Monoclonal Antibody (APC Conjugated) [53.6.7](AGEL0382)")
Mouse CD8a Monoclonal Antibody (APC Conjugated) [53.6.7](AGEL0382)
system_update_altDatasheetOverviewAnti
](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/590x590/products/11211/15265/mouse-cd8a-monoclonal-antibody-percp-conjugated-53.6.7agel0383__98089__90901.1706269402.jpg?c=1 "Mouse CD8a Monoclonal Antibody (PercP Conjugated) [53.6.7](AGEL0383)")
Mouse CD8a Monoclonal Antibody (PercP Conjugated) [53.6.7](AGEL0383)
system_update_altDatasheetOverviewAnti
](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/590x590/products/11206/15260/mouse-cd8a-monoclonal-antibody-53.6.7agel0378__17860__91801.1706269400.jpg?c=1 "Mouse CD8a Monoclonal Antibody [53.6.7](AGEL0378)")