Cell Death Recombinant Proteins
Mouse CD5L Recombinant Protein (RPES0631)
- SKU:
- RPES0631
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Research Area:
- Cell Death
Description
Mouse CD5L Recombinant Protein
CD5L, also known as CD5 antigen-like, is secreted protein which mainly expressed by macrophages in lymphoid and inflammed tissues and regulates mechanisms in inflammatory responses, such as infection or atherosclerosis. It is able to inhibit lipid droplet size in adipocytes. CD5L acts as a key regulator of metabolic switch in T-helper Th17 cells. It is Participates in obesity-associated autoimmunity via its association with IgM, interfering with the binding of IgM to Fcalpha/mu receptor and enhancing the development of long-lived plasma cells that produce high-affinity IgG autoantibodies. It also acts as an inhibitor of apoptosis in macrophages: promotes macrophage survival from the apoptotic effects of oxidized lipids in case of atherosclerosis. It is involved in early response to microbial infection against various pathogens by acting as a pattern recognition receptor and by promoting autophagy.
| Product Name: | Mouse CD5L Recombinant Protein (RPES0631) |
| Product Code: | RPES0631 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | Human Cells |
| Synonyms: | CD5 antigen-like,Apoptosis inhibitor expressed by macrophages,Apoptosis inhibitory 6,CT-2,SP-alpha,Cd5l,Aim, Api6,AAC-11, AI047839, Api6, CT2, Pdp, Sp-alpha |
| Accession: | Q9QWK4 |
| Sequence: | Glu22-VaL352 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse CD5 antigen-like is produced by our Mammalian expression system and the target gene encoding Glu22-VaL352 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by SDS-PAGE |
| Mol Mass: | 37.4 kDa |
| AP Mol Mass: | 52kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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