Mouse CD30/TNFRSF8 Recombinant Protein (RPES3348)

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SKU:
RPES3348
Product Type:
Recombinant Protein
Species:
Mouse

Description

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Mouse CD30/TNFRSF8 Recombinant Protein

CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody responses. CD30 is expressed by activated, but not by resting, T and B cells. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its ligand CD30L (CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis. CD30 has been considered as a specific diagnostic biomarker of anaplastic large cell lymphoma (ALCL) and classical Hodgkin lymphoma (cHL). CD30 is also a biomarker used for targeted therapy by an antibody–drug conjugate. Soluble CD30 retains the ability to bind CD30 Ligand and functions as an inhibitor of normal CD30 signaling.

Product Name:Mouse CD30/TNFRSF8 Recombinant Protein (RPES3348)
Product Code:RPES3348
Size:10µg
Species:Mouse
Expressed Host:Human Cells
Synonyms:Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Lymphocyte activation antigen CD30, CD30, Tnfrsf8
Accession:Q60846
Sequence: Phe19-Thr281
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Mouse TNF Receptor Superfamily Member 8 is produced by our Mammalian expression system and the target gene encoding Phe19-Thr281 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by SDS-PAGE
Mol Mass:28.4 kDa
AP Mol Mass:55-65 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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