Mouse CD3 epsilon monoclonal antibody (PE) (AGIM0236)

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SKU:
AGIM0236
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Hamster
Isotype:
IgG
Clone:
145-2C11
Conjugation:
PE
Applications:
FC

Description

system_update_altDatasheet
Product Name:Mouse CD3e monoclonal antibody (PE)
Product Code:AGIM0236
Size:500 µL
Reactivity:Mouse
Clone:145-2C11
Applications:Flow Cytometry
Conjugate:PE
Isotype:IgG
Host Species:Hamster
Storage:Store at 4°C. Avoid prolonged exposure to light.
Uniprot:P22646
UniProt Protein Function:CD3E: a T cell surface glycoprotein that is a component of the T cell antigen receptor. The recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation. Contains 1 immunoglobulin-like domain and 1 ITAM domain.
UniProt Protein Details:

Protein type:Receptor, misc.; Membrane protein, integral

Cellular Component: T cell receptor complex; membrane; integral to membrane; plasma membrane; immunological synapse; alpha-beta T cell receptor complex; intercellular junction; external side of plasma membrane

Molecular Function:protein binding; signal transducer activity; transmembrane receptor activity; protein heterodimerization activity; SH3 domain binding

Biological Process: positive regulation of interleukin-2 biosynthetic process; lymphocyte activation; positive regulation of calcium-mediated signaling; negative thymic T cell selection; T cell receptor signaling pathway; positive regulation of interleukin-4 production; positive regulation of interferon-gamma production; positive regulation of peptidyl-tyrosine phosphorylation; cell surface receptor linked signal transduction; negative regulation of smoothened signaling pathway; T cell costimulation; positive regulation of alpha-beta T cell proliferation; positive regulation of T cell proliferation; positive regulation of T cell activation; positive regulation of T cell anergy; response to nutrient

UniProt Code:P22646
NCBI GenInfo Identifier:6680886
NCBI Gene ID:12501
NCBI Accession:NP_031674.1
UniProt Related Accession:P22646
Molecular Weight:21,393 Da
NCBI Full Name:T-cell surface glycoprotein CD3 epsilon chain
NCBI Synonym Full Names:CD3 antigen, epsilon polypeptide
NCBI Official Symbol:Cd3e  
NCBI Official Synonym Symbols:CD3; T3e; AI504783; CD3epsilon  
NCBI Protein Information:T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain
UniProt Protein Name:T-cell surface glycoprotein CD3 epsilon chain
UniProt Synonym Protein Names:T-cell surface antigen T3/Leu-4 epsilon chain; CD_antigen: CD3e
Protein Family:CD302 antigen
UniProt Gene Name:Cd3e  
UniProt Entry Name:CD3E_MOUSE
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