Mouse CD3 epsilon Monoclonal Antibody [145-2C11](AGEL0374)

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SKU:
AGEL0374
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Hamster
Isotype:
IgG
Clone:
145-2C11
Conjugation:
Unconjugated
Applications:
FC
Applications:
WB
Applications:
IHC
Applications:
IF
Applications:
IP

Description

system_update_altDatasheet
Antibody Name:Mouse CD3ε Monoclonal Antibody
Antibody Code:AGEL0374
Size:100µg
Clone:145-2C11
Synonyms:T-cell surface glycoprotein CD3 epsilon chain, CD3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T3E
Host Species:Hamster
Species Reactivity:Mouse
Applications:FC, WB, IHC, IF, IP
Concentration:1mg/mL
Isotype:IgG
Conjugation:Unconjugated
Applications:FC, WB, IHC, IF, IP
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:PBS with 0.05% Proclin300
Storage:Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Gene ID:12501
Uniprot:P22646
Background:CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
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