Mouse CD28/TP44 Recombinant Protein (RPES0536)
- SKU:
- RPES0536
- Product Type:
- Recombinant Protein
- Species:
- Mouse
Description
system_update_altDatasheet
Mouse CD28/TP44 Recombinant Protein
T-cell-specific surface glycoprotein CD28, contains an Ig-like V-type domain. CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals, which are required for their activation. It is the receptor for CD80 and CD86. When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. It involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
| Product Name: | Mouse CD28/TP44 Recombinant Protein (RPES0536) |
| Product Code: | RPES0536 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | Human Cells |
| Synonyms: | T-cell-specific surface glycoprotein CD28,CD28,CH29-189K17.3 |
| Accession: | NP_031668.3 |
| Sequence: | Asn20-Lys149 |
| Fusion tag: | C-Fc-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse T-cell-specific surface glycoprotein CD28 is produced by our Mammalian expression system and the target gene encoding Asn20-Lys149 is expressed with a Fc, 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by SDS-PAGE |
| Mol Mass: | 43.0 kDa |
| AP Mol Mass: | 60 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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