Mouse CD209b Monoclonal Antibody [22D1](AGEL0125)
](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/11038/15092/mouse-cd209b-monoclonal-antibody-22d1agel0125__79171__68688.1706269326.jpg?c=1 "Mouse CD209b Monoclonal Antibody [22D1](AGEL0125)")
- SKU:
- AGEL0125
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Hamster
- Isotype:
- IgG
- Clone:
- 22D1
- Conjugation:
- Unconjugated
- Applications:
- FC
- Applications:
- IHC
- Applications:
- IP
](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/11038/15092/mouse-cd209b-monoclonal-antibody-22d1agel0125__79171__68688.1706269326.jpg?c=1&imbypass=on "Mouse CD209b Monoclonal Antibody [22D1](AGEL0125)")
Description
system_update_altDatasheet
| Antibody Name: | Mouse CD209b Monoclonal Antibody |
| Antibody Code: | AGEL0125 |
| Size: | 100µg |
| Clone: | 22D1 |
| Synonyms: | CD209 antigen-like protein B, Cd209b, DC-SIGN-related protein 1, DC-SIGNR1, OtB7, CD209, Cd209b |
| Host Species: | Hamster |
| Species Reactivity: | Mouse |
| Applications: | FC, IHC, IP |
| Concentration: | 1mg/mL |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Applications: | FC, IHC, IP |
| Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Storage Buffer: | PBS with 0.05% Proclin300 |
| Storage: | Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Gene ID: | 69165 |
| Uniprot: | Q8CJ91 |
| Background: | CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway. |
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