Mouse CD183/CXCR3 Monoclonal Antibody (PE/Cyanine5 Conjugated) [CXCR3-173](AGEL1431)

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SKU:
AGEL1431
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
IgG2a,k
Clone:
CXCR3-173
Conjugation:
PE/Cy5

Description

Antibody Name:Mouse CD183/CXCR3 Monoclonal Antibody (PE/Cyanine5 Conjugated)
Antibody Code:AGEL1431
Size:50µg
Clone:CXCR3-173
Synonyms:C-X-C chemokine receptor type 3,Cxcr3,CXC-R3,CXCR-3,Interferon-inducible protein 10 receptor,IP-10 receptor,CD183/CXCR3
Host Species:Armenian Hamster
Species Reactivity:Mouse
Applications:FC
Concentration:1mg/mL
Isotype:IgG2a,k
Conjugation:PE/Cyanine5
Applications:FC
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:PBS with 0.05% Proclin300, 1% BSA
Storage:Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Gene ID:12766
Uniprot:O88410
Background:CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.
Mouse CD19 Monoclonal Antibody (FITC Conjugated)C57BL/6 murine splenocytes are stained with Anti-Mouse CD183/CXCR3 Monoclonal Antibody(PE/Cyanine5 Conjugated) and Anti-Mouse CD3 Monoclonal Antibody(AF488 Conjugated)[Both antibodies are used at 0.2 ?g/106 cells dilution]. Splenocytes stained with Anti-Mouse CD3 Monoclonal Antibody(AF488 Conjugated) (right) are used as control.
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