Mouse CD183/CXCR3 Monoclonal Antibody (PE/Cyanine5 Conjugated) [CXCR3-173](AGEL1423)

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SKU:
AGEL1423
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
IgG2a,k
Clone:
CXCR3-173
Conjugation:
PE/Cy5

Description

Antibody Name:Mouse CD183/CXCR3 Monoclonal Antibody (PE/Cyanine5 Conjugated)
Antibody Code:AGEL1423
Size:50 Tests
Clone:CXCR3-173
Synonyms:C-X-C chemokine receptor type 3,Cxcr3,CXC-R3,CXCR-3,Interferon-inducible protein 10 receptor,IP-10 receptor,CD183/CXCR3
Host Species:Armenian Hamster
Species Reactivity:Mouse
Applications:FC
Concentration:5uL
Isotype:IgG2a,k
Conjugation:PE/Cyanine5
Applications:FC
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:PBS with 0.05% Proclin300, 1% BSA
Storage:Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Gene ID:12766
Uniprot:O88410
Background:CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.
Mouse CD19 Monoclonal Antibody (FITC Conjugated)C57BL/6 murine splenocytes are stained with Anti-Mouse CD183/CXCR3 Monoclonal Antibody(PE/Cyanine5 Conjugated) and Anti-Mouse CD3 Monoclonal Antibody(AF488 Conjugated)(left). Splenocytes stained with Anti-Mouse CD3 Monoclonal Antibody(AF488 Conjugated) (right) are used as control.
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