Name: Mouse CD161/NK1.1 Monoclonal Antibody (APC Conjugated) [PK136](AGEL0486)
SKU: AGEL0486
Availability: OutOfStock

Mouse CD161/NK1.1 Monoclonal Antibody (APC Conjugated) [PK136](AGEL0486)

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SKU:

AGEL0486

Product Type:

Antibody

Antibody Type:

Monoclonal Antibody

Applications:

Reactivity:

Mouse

Host Species:

Mouse

Isotype:

IgG2a,k

Clone:

PK136

Conjugation:

APC

Description

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OverviewAntibody Name:Mouse CD161/NK1.1 Monoclonal Antibody (AF488 Conjugated)Antibody Code:AGEL0492Size:50µgClone:PK136

Concentration:	1mg/mL
Isotype:	IgG2a,k
Conjugation:	APC
Applications:	FC
Recommended Dilution:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:	PBS with 0.05% Proclin300, 1% BSA
Storage:	Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.

Gene ID:	17059
Uniprot:	P27814
Background:	NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.