Mouse CD160/BY55 Recombinant Protein (RPES2051)
- SKU:
- RPES2051
- Product Type:
- Recombinant Protein
- Species:
- Mouse
Description
Mouse CD160/BY55 Recombinant Protein
CD160 antigen is a cell membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain. CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed in spleen, peripheral blood, and smal lintestine. Expression of CD160 is restricted to functional NK and T cytotoxic lymphocytes. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. Activated NK lymphocytes release a soluble form of CD160 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness.
| Product Name: | Mouse CD160/BY55 Recombinant Protein (RPES2051) |
| Product Code: | RPES2051 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | Human Cells |
| Synonyms: | CD160 Antigen, Natural Killer Cell Receptor BY55, CD160, BY55 |
| Accession: | Q8VC80 |
| Sequence: | Gly28-Ser160 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse CD160 is produced by our Mammalian expression system and the target gene encoding Gly28-Ser160 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 15.8 kDa |
| AP Mol Mass: | 20-25 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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