Name: Mouse CD150 Monoclonal Antibody (APC Conjugated) [TC15-12F12.2](AGEL1884)
SKU: AGEL1884
Availability: OutOfStock

Mouse CD150 Monoclonal Antibody (APC Conjugated) [TC15-12F12.2](AGEL1884)

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SKU:

AGEL1884

Product Type:

Antibody

Antibody Type:

Monoclonal Antibody

Applications:

Reactivity:

Mouse

Host Species:

Rat

Isotype:

IgG2a,k

Clone:

TC15-12F12.2

Conjugation:

APC

Description

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OverviewAntibody Name:Mouse CD150 Monoclonal Antibody (APC Conjugated)Antibody Code:AGEL1882Size:100 TestsClone:TC15-12F12.2

OverviewAntibody Name:Mouse CD150 Monoclonal Antibody (PE Conjugated)Antibody Code:AGEL1883Size:50µgClone:TC15-12F12.2

OverviewAntibody Name:Mouse CD150 Monoclonal Antibody (PE Conjugated)Antibody Code:AGEL1881Size:100 TestsClone:TC15-12F12.2

OverviewProduct Name:FITC Anti-Mouse CD150 Antibody [TC15-12F12.2]Product Code:AGEL2300Clone No:TC15-12F12.2Synonyms:Slam,Slamf1,

OverviewProduct Name:AF647 Anti-Mouse CD150 Antibody [TC15-12F12.2]Product Code:AGEL3371Size:25ug, 100ugClone No:TC15-12F12.2

Concentration:	1mg/mL
Isotype:	IgG2a,k
Conjugation:	APC
Applications:	FC
Recommended Dilution:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:	PBS with 0.05% Proclin300, 1% BSA
Storage:	Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.

Gene ID:	27218
Uniprot:	Q9QUM4
Background:	CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.