Name: Mouse CD150 Monoclonal Antibody (APC Conjugated) [TC15-12F12.2](AGEL1882)
SKU: AGEL1882
Availability: OutOfStock

Mouse CD150 Monoclonal Antibody (APC Conjugated) [TC15-12F12.2](AGEL1882)

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SKU:

AGEL1882

Product Type:

Antibody

Antibody Type:

Monoclonal Antibody

Applications:

Reactivity:

Mouse

Host Species:

Rat

Isotype:

IgG2a,k

Clone:

TC15-12F12.2

Conjugation:

APC

Description

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OverviewAntibody Name:Mouse CD150 Monoclonal Antibody (APC Conjugated)Antibody Code:AGEL1884Size:50µgClone:TC15-12F12.2<

OverviewAntibody Name:Mouse CD150 Monoclonal Antibody (PE Conjugated)Antibody Code:AGEL1883Size:50µgClone:TC15-12F12.2

OverviewAntibody Name:Mouse CD150 Monoclonal Antibody (PE Conjugated)Antibody Code:AGEL1881Size:100 TestsClone:TC15-12F12.2

OverviewProduct Name:FITC Anti-Mouse CD150 Antibody [TC15-12F12.2]Product Code:AGEL2300Clone No:TC15-12F12.2Synonyms:Slam,Slamf1,

OverviewProduct Name:AF647 Anti-Mouse CD150 Antibody [TC15-12F12.2]Product Code:AGEL3371Size:25ug, 100ugClone No:TC15-12F12.2

Concentration:	5uL
Isotype:	IgG2a,k
Conjugation:	APC
Applications:	FC
Recommended Dilution:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:	PBS with 0.05% Proclin300, 1% BSA
Storage:	Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.

Gene ID:	27218
Uniprot:	Q9QUM4
Background:	CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.