Description
Antibody Name: | Mouse CD14 Monoclonal Antibody (PE Conjugated) |
Antibody Code: | AGEL1873 |
Size: | 50µg |
Clone: | Sa14-2 |
Synonyms: | CD 14,Myeloid cell-specific leucine-rich glycoprotein,Monocyte differentiation antigen CD14 |
Host Species: | Rat |
Species Reactivity: | Mouse |
Applications: | FC |
Concentration: | 1mg/mL |
Isotype: | IgG2a,k |
Conjugation: | PE |
Applications: | FC |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. |
Gene ID: | 12475 |
Uniprot: | P10810 |
Background: | CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens. |
Mouse abdominal macrophages elicited by starch broth are stained with Anti-Mouse CD14 Monoclonal Antibody(PE Conjugated))[Used at 0.05 ?g/106 cells dilution](filled gray curve). Unstained macrophages (blank black curve) are used as control. |